A total of 37 SHs were mapped on canonical pathways with the most contributing SHs related to triacylglycerol degradation, retinol biosynthesis, heparan sulfate biosynthesis (late stages), xenobiotic metabolism PXR signaling pathway, SPRINK1 pancreatic cancer pathway, phospholipases and stearate biosynthesis (animals). Here, NR1I2 is linked to familial pancreatic carcinoma.