Regarding the comparison of the present case study with the dataset of angiosarcomas from different anatomical locations (GSE163359), altered expressions were found in common in the two datasets as CFD, ADH1B, ALDH2, MAOA, TMEM132C, GREM2, CLEC3B, PTPRT, CES4A, ADORA1, DLK1, DIO3, ENTPD3, EDN3, C1QTNF7, FRMD1; these results could indicate a dysregulation metabolic pathway in common among angiosarcomas. Here, CES4A is linked to angiosarcoma.