Comparing the results of Wei et al., 2022 and the present angiosarcoma case report, 20 genes with differential expression are observed in common: six over-expressed (PRKAA2, CBS, RAB17, PCSK6, RET, HOXA9, SLC4A11) and fourteen down-regulated genes (SORBS1, NRGN, ASPN, DUSP1, GHR, SVEP1, FOSB, TIMP4, ITGAX, TYROBP, FOS, IL1B, PTGS2, NR4A3). The gene discussed is PRKAA2; the disease is angiosarcoma.