To explore the potential mechanism of the TIGAR in the metabolism and apoptosis, we detected the mRNA level (Figure 3b) and protein level (Figure 3c) of the TIGAR by qPCR and Western blotting, respectively, after the cisplatin treatment and/or p53 transfection in a lung cancer A549 cell line for 24 h. The gene discussed is TP53; the disease is lung carcinoma.