For example, cyanidin-3-O-glucoside (C3G) could increase PTEN-induced kinase 1 (PINK1)/Parkin expression and mitochondrial localization to suppress hepatic oxidative stress, NLR family pyrin domain containing 3 (NLRP3) inflammasome activation, steatosis and improve systemic glucose metabolism in mice with NAFLD [30]. This evidence concerns the gene PRKN and metabolic dysfunction-associated steatotic liver disease.