Additionally, although it was expected that a decrease in the GVHD effect would be associated with a concordant reduction in the graft-versus-leukemia (GVL) effect, no difference was observed in the incidence of relapse between recipients of an IL-10-1082GG vs. AA graft in the MUD, MRD, or total patient groups (Figure 2). The gene discussed is IL10; the disease is leukemia.