Transforming growth factor-β (TGFβ), interleukin 7 (IL-7), and hepatocyte growth factor (HGF), all produced by MM cells, are also involved in OB differentiation, reducing the levels of Runt-related transcription factor 2 (RUNX2) and bone morphogenetic protein (BMP) [14,15,16]. Here, HGF is linked to Miyoshi myopathy.