TP53 and breast adenocarcinoma: Interestingly, the new band was induced by DNA damage (treatment with etoposide (Eto)) in LN299 cells (Figure 2D) and endoplasmic reticulum (ER) stress (treatments with thapsigargin (Th) and tunicamycin (Tu)) in wt p53 breast adenocarcinoma cells MCF7 (Figure 2E), which suggests this protein may play a role in stress response.