An important step was also the identification of miRNAs significantly differentiating endometrial cancer from the control and further prediction of which of them may regulate their expression of peroxiredoxin 2 (PRDX2), polycystin 2 (PKD2), aquaporin 1 (AQP1), superoxide dismutase 3 (SOD3), and Krueppel-like factor 2 (KLF2). The gene discussed is KLF2; the disease is endometrial cancer.