MAPK8 and Anxiety: ↓ Anxiety-related behaviour.Improved spatial learning and memory (MWM).↑ Brain insulin signalling.↓ p-JNK activation.↓ Hippocampal and cortical Aβ deposition.↓ Soluble Aβ40 and Aβ42 levels.↑ Hippocampal neurogenesis.