Our previous studies on human peripheral blood-derived CD34+-enriched hematopoietic stem and progenitor cells suggested that other hormones, such as thyroid hormones or growth hormones, released in an excessive manner due to specific endocrinopathies could play a role in the regulation of the growth, survival, and apoptosis of human early hematopoietic stem cells [6,7,8], thus potentially affecting the peripheral blood cell counts, abnormalities of which are observed concurrently in different endocrine dysfunctions in humans. The gene discussed is CD34; the disease is endocrine system disorder.