More specifically—while both foz/foz C57BL/6 and foz/foz BALB/c mice were similarly obese-hepatomegaly, hyperinsulinemia, hyperglycemia, and lower adiponectin levels occurred only in foz/foz C57BL/6 mice and not in foz/foz BALB/c mice after consuming either chow diet or HFD [63]. The gene discussed is ADIPOQ; the disease is hyperinsulinism.