EPB41L4A and breast cancer: For instance, Pang et al. demonstrated that ZNF217 recruits EZH2 to the lncRNA EPB41L4A-AS2 locus and suppresses lncRNA EPB41L4A-AS2 expression by epigenetically increasing trimethylated histone H3 at lysine 27 (H3K27me3) enrichment, thus promoting BC cell proliferation, migration, and invasion [95].