For example, Gao et al. found that lncRNA PTENP1 acts as an miR-20a endogenous sponge to positively regulate the gene of phosphate and tension homology deleted on chromosome ten (PTEN) expression, inhibiting BC progression by the PTENP1/miR-20a/PTEN axis; the deregulation of lncRNA PTENP1 can promote BC progression [28]. This evidence concerns the gene PTEN and breast cancer.