A later study, however, reported that there were no significant differences in TMEM106B genotypes or hexanucleotide lengths of C9orf72 between PSP/CBD patients with and without TDP-43 pathology [80]; this may suggest that comorbidity of TDP-43 pathology is not derived by only a single genetic factor. This evidence concerns the gene TARDBP and supranuclear palsy, progressive, 1.