Apigenin in doses equivalent to human consumption in a healthy diet (20–50 μg/day via oral gavage) significantly reduced the growth of prostate cancers in mice, inhibited NF-κB p50 and p65 phosphorylation, and decreased phosphorylation and degradation of IκBα in a dose-dependent manner [197]. The gene discussed is NFKB1; the disease is prostate carcinoma.