Thus, the omics approach based on SEC and label-free quantitative MS profiling made it possible to catalog stable nuclear protein complexes isolated from the human glioblastoma cell line T98G with partial verification by an independent method of direct interactions of a number of proteins co-fractionated with histone deacetylase 1 (HDAC1) [55]. This evidence concerns the gene HDAC1 and glioblastoma.