Nuclear p-NFκB-p65 expression was generally higher in BC cells in bone metastases compared to primary BC tissue (Figure 5B,D), whereas the same tissue samples previously stained for PEDF showed an opposite trend and nuclear PEDF expression was higher in BC cells in the primary tumour compared to BC cells in bone metastases tissue (Figure 5A,C, Table 2). The gene discussed is SERPINF1; the disease is breast cancer.