Emphasizing the lack of research models for radioinduced OM and the lack of studies that evidence the action of PBMT in OM at the cellular level, this work aimed to evaluate the PBMT action on OM induced in rats tongue, by single dose of 20 Gray (Gy) from a gamma ray source, in relation to the expression of CK10 and 14 during OM repair. This evidence concerns the gene KRT10 and ocular melanoma.