CD47 and central nervous system cancer: Blockage of the anti-phagocytic CD47-SIRPα axis using an anti-CD47 antibody, Hu5F9-G4, strongly induced BMDM-mediated phagocytosis of glioma cells, and mice treated with Hu5F9-G4 demonstrated significant longer survival [30] (Figure 1, Molecular event 9).