These authors demonstrated that GBM which contain a higher number of polymorphonuclear leukocytes/granulocytes (GBM-hPMNL) are also characterised by increased levels of CD163, TEK (TIE2), HIF1α, VEGF, CXCL2 and ANPEP (CD13). The gene discussed is ANPEP; the disease is glioblastoma.