FASN and cancer: Moreover, we found that FASN expression was significantly positively correlated with monocytes, M0 macrophages in a variety of cancers (STAD, SKCM, SARC, OV, LUSC, LUAD, KIRC, HNSC, CHOL), and that M2 macrophages, which normally exert anti-inflammatory effects in tumors, were also significantly positively correlated with THYM, THCA, TGCT, KIPAN, BRCA, (Figure 4D,E), suggesting that FASN may be involved in the process of monocyte-to-macrophage differentiation and M2-macrophage-mediated anti-inflammatory effects in tumors.