GJC2 and Alzheimer disease: Contrary to our study, in the ventral posteromedial (VPM) nucleus of the thalamus and the primary/secondary motor (MOp/Mos) areas of the cortical layer V of the brain in nine-month-old 5xFAD mice, a reduction in Cx47 immunoreactivity in mature oligodendrocytes near Aβ plaques was noted, which was attributed to severe astrogliosis and AD-induced pathology [1,39,62].