LEP and primary cutaneous T-cell non-Hodgkin lymphoma: Moreover, SNPs in LEP 2548GA have not been suggested to increase the risk of cutaneous T cell lymphomas (TCL) but may be involved in the pharmacogenetic of different treatments for this disease since patients with AG or GG genotypes (with lower plasma leptin levels) could better respond to topical steroids (male patients) and phototherapy (female counterparts) compared with AA patients [204].