Studies related to the sensory pathways of SOD1 transgenic mice, the most commonly used murine model of ALS, have demonstrated pathological changes in the axons of the dorsal columns, the dorsal horn of the spinal cord, and dorsal root, and in the soma of DRG neurons [94,95], similar to what is observed in Wallerian degeneration. Here, SOD1 is linked to amyotrophic lateral sclerosis.