However, after supplementation with HB, HB-1, HB-2, and HB-3, the TC, TG, LDL-C, AST, and ALT levels were significantly reduced, while the HDL-C levels increased, indicating that HB-3 especially improved the hyperlipidemia and liver injury in the HFCD mouse model. The gene discussed is GPT; the disease is hyperlipidemia.