PLPPR1 and urinary tract infection: Besides, PLPPR1 (Log2FC = −2.711, FDR = 5 × 10−5), a gene of member plasticity-related gene (PRG) family and UMOD (Log2FC = −1.61 × 10−8, FDR = 5.64 × 10−7) which is the most abundant protein in mammalian urine under physiological conditions and its urine excretion may defend against urinary tract infections caused by uro-pathogenic bacteria [33,34].