After multivariate Cox analysis, advanced tumor stage (HR: 2.34, 95% CI: 1.37–4.00, p = 0.002) and total deletion or one copy of the ADAM3A and ADAM5 pseudogenes (HR: 1.68, 95% CI: 1.07–2.66, p = 0.02) were found to be predictors of poor EFS (Table 3). This evidence concerns the gene ADAM5 and neoplasm.