The twenty miR-181c-5p targets significantly predicted in this study, “PLAC8, KBTBD11, CXCL12, FOS, MME, FBXL3, KMO, EGR1, DCN, BCHE, LIFR, CYP26A1, HSD11B1, CYP2C8, TMEM27, ITLN1, GPM6A, CNDP1, GYS2, and INMT” were downregulated in HCC [52]. This evidence concerns the gene KBTBD11 and hepatocellular carcinoma.