As shown in Figure 8C, the AUCs of CCNB, CDK1, BUB1B, ECT2, RACGAP1, ANLN, PBK, TOP2A, ASPM, RRM2, NEK2, PRC1, SPP1, HMMR, and DTL were, respectively, 0.980, 0.978, 0.962, 0.946, 0.980, 0.967, 0.964, 0.973, 0.972, 0.961, 0.971, 0.981, 0.724, 0.969, and 0.961, which indicated that these 15 hub genes could efficiently discriminate tumor and normal samples and show a satisfactory performance in survival prediction. The gene discussed is BUB1B; the disease is neoplasm.