As shown in Figure 8C, the AUCs of CCNB, CDK1, BUB1B, ECT2, RACGAP1, ANLN, PBK, TOP2A, ASPM, RRM2, NEK2, PRC1, SPP1, HMMR, and DTL were, respectively, 0.980, 0.978, 0.962, 0.946, 0.980, 0.967, 0.964, 0.973, 0.972, 0.961, 0.971, 0.981, 0.724, 0.969, and 0.961, which indicated that these 15 hub genes could efficiently discriminate tumor and normal samples and show a satisfactory performance in survival prediction. Here, SPP1 is linked to neoplasm.