IGF1 and colorectal cancer: In the Metascape analysis, the GO produced a list of top-level biological processes and a heatmap of enriched terms related to the input genes, which included: “Epithelial to mesenchymal transition in colorectal cancer”, “Tissue morphogenesis”, “Burn wound healing”, “Establishment of cell polarity”, “Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling”, “PID MYC repress pathway”, “Negative regulation of cell differentiation” (Figure 2A).