MMP2 and brain disorder: Among these 15 EMT genes, MMP2, MAP1B, SNAI2, and WNT5A stand out for their relationship with neoplasms and brain disorders, and are thus termed neuronal EMT genes, and with different chemicals, including platinum-based chemotherapy and tyrosine–kinase inhibitors, which affect the expression of these genes and have been identified with an antineoplastic effect.