There are 26 genes in the ensemble meta-classifier, including genes involved in skin cell differentiation (CLEC2A, KRT6B, KRT14, KRT17, KRTDAP), immunity (S100A7, S100A7A, IL20RB, C7, PRG2, SERPINB4, WFDC5, FKBP1B), cell adhesion (PVRL4), energy/metabolism (PC, TSHR), cancer metastasis (AFAP1-AS1) and suppression (DMBT1), cellular redox (GSR), cell signaling (GNG2), cell division (ZSWIM7), protein synthesis and modification (RPS28, RPN2), and transcriptional regulation (ZNF653, PAX1). This evidence concerns the gene ZNF653 and cancer.