We also proposed potential candidate genes in four cases (~14%) without known macrocephaly gene within the CNV (Table 2): in one case, the detected CNV encompassed a known microcephaly gene (TRAPPC9), and in three others, the RALGAPB, RBMS3, and ZDHHC14 genes were highlighted, mainly based on an in silico analysis of their functional roles, as described in Table 2. Here, RBMS3 is linked to Macrocephaly.