A high expression of GSDMB was associated with a low survival rate and a high metastasis rate in breast cancer [16,17], a high level of GSDMD in lung adenocarcinoma was associated with a poor prognosis, while GSDMD could inhibit tumor proliferation and was related with favorable prognosis in non-smallcell lung cancer [18]. Here, GSDMD is linked to lung adenocarcinoma.