EGFR and non-small cell lung carcinoma: Furthermore, Liu et al. [78] demonstrated that EGFR-TKIs plus chemotherapy (pemetrexed, gemcitabine plus cisplatin, or carboplatin) significantly improve ORR and prolong median PFS and OS compared with EGFR-TKIs alone in patients with EGFR-mutated NSCLC and BIM deletions.