Among these, the mRNA expression of BUB3, DHX9, PRMT1, THOC4, THOC7, U2AF1, and ZNF207 (BUGZ) were found to increase in several primary tumors compared to healthy tissues, while SRSF1 (ASF/SF2) was downregulated in most cancers (except for acute myeloid leukemia—LAML). The gene discussed is SRSF1; the disease is acute myeloid leukemia.