PRMT1 and cancer: Moreover, the expression of some of these R-loop-binding proteins was found to be directly linked to patient survival in various cancers, e.g., a low level of RNASEH2A, THOC6, PRMT1, and PIF1 were associated with prolonged survival in mesothelioma patients (MESO), while a low FANCM mRNA level appeared advantageous for breast cancer survival (Figure 2C).