KIF12 and cirrhosis, familial: Further diagnoses in order of frequency were progressive familial intrahepatic cholestasis (PFIC) (20%), cystic fibrosis (7.7%), cryptogenic cirrhosis (7.7%), Alagille syndrome (6.2%), metabolic conditions (4.6%), hepatic malignancy (1.5%), acute liver failure (1.5%), primary sclerosing cholangitis (1.5%), KIF12 variant, identified as a cholestasis-associated candidate gene, (1.5%) [17], and alpha-1 antitrypsin deficiency (1.5%).