As a result, PSA velocity and PSA value were significantly correlated with the number of involved bone, lymph node and soft tissue lesions in univariable analysis, but multivariable analysis confirmed PSA value as an independent predictor of the number of bone lesions (IRR 1.003, p  =  0.0002). The gene discussed is KLK3; the disease is short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome.