TP53 and idiopathic pulmonary fibrosis: Interestingly, genes supporting the inflammation and fibrogenesis in IPF, such as TGF-β1, interleukin-1 receptor alpha (IL1RN), interleukin 8 (IL-8), Toll-like receptor 3 (TLR3), telomerases, tumor protein 53 (TP53), are also associated with cancer.