The neurofilament light chain (NfL), phosphorylated neurofilament heavy chain (pNfH) and chitinase-3-like protein 1 (YLK-40) were described as statistically significant CSF differentiating biomarkers to discriminate tauopathies and synucleinopathies [31]. This evidence concerns the gene CHI3L1 and synucleinopathy.