While the worldwide data shows a 4–5% prevalence rate of NUP98::NSD1 in pediatric AML and 1.3–3% in adult AML [9,10,11,12], we found that the percentage prevalence of NUP98::NSD1 fusion transcript in our pediatric was 7.89% (3/38), which was comparatively higher than reported previously. The gene discussed is NUP98; the disease is acute myeloid leukemia.