HOXB6 and acute myeloid leukemia: We also found that HOX genes were highly upregulated in all the NUP98::NSD1 patients, specifically HOX A1, HOXA3, HOXA5, HOXA6, HOX A7, HOX A9, HOX A10, and HOXB6 expression, suggesting that the alteration is conserved in our AML patients with NUP98::NSD1.