The spectrum of SRGs implicated in inheritable PF was further expanded by the observation that bi-allelic mutations in the gene of ATP-binding cassette subfamily A, member 3 (ABCA3) protein, which plays a cardinal role in surfactant homeostasis, are associated with neonatal respiratory distress syndrome (RDS) and in “chILD” surviving into adulthood [77,78,79,80]. Here, ABCA3 is linked to interstitial lung disease specific to childhood.