The overexpression of CAT may also dampen H2O2 signalling and sensitise human and animal cells to different stressors (e.g., hepatocytes and fibroblasts, alveolar macrophages) or reduce the growth of cells (e.g., rat aortic smooth muscle cells, human aortic endothelial cells, human MCF-7 breast cancer cells, A-375 amelanotic melanoma cells, human promyelocytic HL-60 cells) [93,162,163,164,165]. Here, CAT is linked to breast cancer.