CNR1 and atopic eczema: In addition, AEA and the newly synthesised CB1 agonists α-oleoyl oleoylamine ethanolamine (α-OOE; Figure 1) and α-OOS (Figure 1) suppressed mast cell proliferation, inhibited the release of inflammatory mediators and prevented the increase of skin fold thickness in mice with oxazolone-induced atopic dermatitis mice.