MTOR and cancer: In addition to cell death induction, UA can limit cancer growth through its anti-proliferative and anti-invasive effects, for example, by inhibiting the cancer-promoting transcription factors, Nuclear Factor-κB (NF-κB) [10,11] and Signal Transducer and Activator of Transcription 3 (STAT3) [12], or the mammalian Target Of Rapamycin (mTOR) signaling pathway [13].