In addition, sEVs from CAFs with high miR-92a-3p expression activated the Wnt/βcatenin pathway in CRC cells, inhibiting mitochondrial apoptosis by directly inhibiting FBXW7 and MOAP1 expression and promoting EMT in CRC cells, thus further facilitating metastasis [50]. Here, FBXW7 is linked to colorectal carcinoma.