Higher mRNA expression levels of RHOA (p = 0.001), RHOC (p < 0.001), RHOD (p < 0.001), RHOF (p < 0.001), RHOJ (p < 0.001), RHOQ (p = 0.001), RHOU (p < 0.001), RHOV (p < 0.001), RAC1 (p < 0.001), RAC3 (p < 0.001), RND1 (p < 0.001), RND2 (p < 0.001), and RND3 (p < 0.001) were observed, while lower mRNA expression levels of RHOB (p = 0.002) and RHOG (p < 0.001) were seen in DLBCL. This evidence concerns the gene RHOA and diffuse large B-cell lymphoma.