KEGG terms of specifically upregulated genes in CSF1R monocytes in these four testudines were enriched in biological pathways for oxidative phosphorylation, disease (Parkinson’s disease, non-alcoholic fatty liver disease, Huntington’s disease, Alzheimer’s disease, etc.), and lysosomes (Figure 5). This evidence concerns the gene CSF1R and early-onset autosomal dominant Alzheimer disease.