The fatal clinical course of human glioblastoma despite aggressive adjuvant therapies is due to highly resistant tumor cells, i.e., glioma stem cells (GSC), which express ALDH1 [3], and ALDH1 seems to be involved in the biological processes that lead to therapy resistance by interacting with lipid peroxidation (LPO) [5]. The gene discussed is ALDH1A1; the disease is glioblastoma.