We recently showed that in individuals without T2D, adipose SRA1 expression was significantly higher in obese people compared with normal weight people and the adipose tissue SRA1 expression associated directly with metabolic markers including body mass index (BMI), percentage of body fat (PBF), serum insulin, homeostasis model assessment of insulin resistance (HOMA-IR), proinflammatory cytokines and chemokines or their receptors including C-X-C motif ligand-9 (CXCL9), CXCL10, CXCL11, TNFα, transforming growth factor-β (TGFβ), IL2RA, and IL18, but inversely with CCL19 and CCR2 expression. This evidence concerns the gene IL18 and type 2 diabetes mellitus.