IRF3 and obesity due to melanocortin 4 receptor deficiency: Regarding the association between adipose SRA1 gene expression and meta-inflammatory markers studied (Table 3), we found that SRA1 correlated with TLR2 (r = 0.317, p = 0.017), TLR3 (r = 0.531, p < 0.0001), TLR4 (r = 0.311, p = 0.022), TLR7 (r = 0.305, p = 0.015), TLR9 (r = 0.374, p = 0.002), MyD88 (r = 0.324, p = 0.010), IRAK1 (r = 0.255, p = 0.044), NF-κB (r = 0.454, p < 0.001), IRF3 (r = 0.290, p = 0.030) and IRF5 (r = 0.321, p = 0.010) expression in individuals with obesity.