More specifically, the expression of NLRP1, NLRP3, NLRP6, NLRC4, CASP1, CASP3, CASP4, CASP5, CASP6, CASP8, CASP9, GSDMA, GSDMC, GSDMD, GSDME, PYCARD, PRKACA, AIM2, NOD1, NOD2, GPX4, TIRAP, SCAF11, PLCG1, TNF, IL1B, and IL18 was increased in LGG relative to non-carcinoma samples, whereas the expression of NLRP2, NLRP7, GSDMB, ELANE, and IL6 was decreased (Figure 2). The gene discussed is GSDME; the disease is carcinoma.