SREBF1 and metabolic dysfunction-associated steatotic liver disease: Upregulation of the lncRNA Gm15622 in NAFLD caused by HFD was examined in a study that discovered that Gm15622 could sponge miR-742-3p, boosting the quantity of SREBP-1 protein, a transcription factor that controls the expression of genes that govern the production of fatty acids, lipids, and cholesterol.