As shown in Figure 3D, EZH2 was positively correlated with CD274 (PD-L1), PDCD1 (PD-1), CTLA4, LAG3, GZMB, and PDCD1LG2 (PD-L2) in NSCLC, showing statistical significance. This evidence concerns the gene CTLA4 and non-small cell lung carcinoma.